KMID : 0939920110430030199
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´ëÇѾÏÇÐȸÁö 2011 Volume.43 No. 3 p.199 ~ p.203
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Successful Chemotherapy Following Autologous Stem Cell Transplantation in Multiple Myeloma and Multi-organ Dysfunction with Infiltration of Eosinophils: A Case Report
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Lee Ho-Sup
Park Lee-Chun Shin Seong-Hoon Lee Sang-Uk Chang Hee-Kyung Huh Bang Jung Gyoo-Sik Kim Yang-Soo
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Abstract
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Eosinophils are derived from hematopoietic stem cells. Peripheral blood eosinophilia is defined as an absolute eosinophil count of ¡Ã0.5¡¿109/L. Eosinophilia is classified into primary or clonal eosinophilia, secondary eosinophilia, and idiopathic categories including idiopathic hypereosinophilic syndrome. Both hematopoietic and solid neoplasms may be associated with peripheral blood eosinophilia, but multiple myeloma is rarely associated with eosinophilia. We now report the case of a 31-year-old man with multiple myeloma associated with marked eosinophilia who developed multiple organ dysfunction with infiltration of eosinophils. He recovered after treatment with chemotherapy followed by autologous stem cell transplantation.
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KEYWORD
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Eosinophilia, Multiple myeloma, Autologous transplantation
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